Top 10 Blockchain Healthcare Companies Setting New Standards in 2025

The global healthcare industry is facing mounting challenges, ranging from data security breaches, lack of transparency, and rising operational costs to fragmented patient data management. In response, leading companies are embracing blockchain healthcare solutions to streamline operations, improve patient care, and secure sensitive data. According to a recent report, the blockchain in healthcare market was valued at USD 7.13 billion in 2023 and is projected to reach USD 595.31 billion by 2032, growing at a CAGR of 63.5%. 

But who is leading the way in this digital revolution?

In this blog, we unveil the list of top 10 companies using blockchain in healthcare to achieve next-level innovation in 2025. These trailblazers are not just experimenting, but they are setting new benchmarks in how blockchain can redefine healthcare.

Why Are Healthcare Companies Turning to Blockchain?

The healthcare industry deals with massive volumes of sensitive, fragmented, and error-prone data. Blockchain’s decentralized, immutable, and transparent nature addresses these challenges head-on. 

Here’s why top healthcare companies are aggressively investing in blockchain healthcare solutions:

• Enhanced Data Security: Blockchain encrypts patient data and ensures only authorized access.
• Improved Interoperability: Blockchain bridges the gap between different healthcare systems.
• Reduced Costs: Automating claims, payments, and record management through smart contracts lowers administrative expenses.
• Transparency & Trust: Patients and regulators can trace every data entry and update.
• Compliance Assurance: Blockchain helps healthcare providers comply with different regulatory mandates.

Explore the List of Top 10 Blockchain Healthcare Companies 

The following is the list of leading blockchain healthcare companies that are transforming the way patient data is managed, shared, and secured.

1. Pfizer 

Pfizer is one of the renowned companies using blockchain in healthcare. The company utilizes the power of blockchain through the MediLedger Project to streamline the complex chargeback process in pharmaceutical distribution. With multiple intermediaries in the supply chain and contracts managed separately, chargebacks often cause costly discrepancies. Pfizer leverages the decentralized network to reduce errors, lower operational costs, and improve overall supply chain efficiency, ultimately contributing to better patient care. This innovation reflects Pfizer’s commitment to embracing cutting-edge technology to solve business inefficiencies and collaborate securely with industry partners.

2. Avaneer Health

Avaneer Health is one of the leading blockchain healthcare companies, which makes data sharing in healthcare easier and safer. Launched in 2020, it’s built on blockchain and FHIR technology to improve transparency and smooth information exchange between healthcare providers. Backed by big names like Cleveland Clinic, Aetna, Anthem, and IBM, Avaneer Health focuses on simplifying processes like eligibility checks, prior authorizations, and payer-to-payer data exchange. Their goal is to create a connected healthcare network that benefits everyone, making care faster, more efficient, and patient-friendly while reducing the usual paperwork and delays.

3. Patientory

Patientory is transforming healthcare with its smart use of blockchain technology. Their flagship product, the Neith Analytics dashboard, easily connects with popular EHR systems like Epic and Cerner to give healthcare providers secure, real-time access to patient data. This helps doctors and hospitals make better, faster decisions. Additionally, Patientory’s partnership with Google MedLM is making it convenient for pharmaceutical companies to find patients for clinical trials and submit proposals to the FDA. Blockchain with advanced analytics enables Patientory to make healthcare more efficient, secure, and focused on patient needs.

4. Cardinal Health Inc. 

Cardinal Health, a global leader in healthcare products and services, is embracing blockchain healthcare solutions to simplify pharma supply chains. With years of experience and operations in 40+ countries, they partnered with Chronicled on the MediLedger Network to boost efficiency and transparency. This blockchain healthcare solution helps Cardinal Health streamline complex chargeback processes and ensures pharmacies get what they need without delays. More importantly, it strengthens connections between suppliers and customers, which makes the entire pharmaceutical supply chain smoother, faster, and more reliable for everyone involved. It’s a smart move toward hassle-free healthcare logistics.

5. GuardTime Health

Guardtime Health leverages blockchain to enhance data integrity and security in the healthcare sector. Their Health Information Exchange (HSX) platform enables seamless, secure data sharing among patients, providers, payers, and regulators and ensures a single, trustworthy version of health data. Additionally, Guardtime developed VaccineGuard, a digital platform connecting stakeholders in the vaccine ecosystem to detect counterfeits, manage vaccination campaigns, and provide real-time insights for public health authorities. Guardtime Health utilizes blockchain technology to foster transparency, trust, and efficiency in healthcare data management

6. Change Healthcare

Change Healthcare has taken a smart step by joining the league of leading blockchain healthcare companies. They’ve integrated blockchain into their Intelligent Healthcare Network™, making them the first to roll out blockchain at an enterprise scale in healthcare. This strategic move of the company boosts transparency in claims management, which enables real-time tracking and smoother revenue cycle operations. Using Hyperledger Fabric™, they’re tackling big industry challenges like inefficiencies and lack of trust. With over 50 million claims processed daily, Change Healthcare is setting a new benchmark for how blockchain healthcare companies can simplify processes and improve patient experiences.

7. Anthem Inc

Anthem Inc. understands how frustrating it can be when medical information isn’t easily accessible, so they’re using blockchain to fix that. With blockchain’s transparency and security, Anthem is creating a trusted way to exchange patient data quickly and safely. This approach removes information barriers and gives patients a smoother, hassle-free experience. By tapping into advanced technology like cryptography and decentralized networks, Anthem is working to modernize healthcare and ensure better, faster, and more reliable care for everyone.

8. Mayo Clinic

Mayo Clinic, one of the most trusted names in healthcare, has teamed up with Dutch blockchain startup Triall to bring a tech-driven approach to clinical trials. Together, they’re using blockchain technology to make clinical trial data more secure and reliable. Triall’s eClinical platform creates a digital, unchangeable audit trail, meaning once the data is recorded, it can’t be tampered with. This helps everyone involved, researchers, regulators, and even patients, trust that the information is accurate and transparent. It’s a smart move that’s setting a new standard for how clinical trial data is managed and shared.

9. UnitedHealth Group

UnitedHealth Group is making smart use of blockchain in healthcare through its partnership in the Synaptic Health Alliance. This alliance brings together big names like UnitedHealthcare, Optum, Humana, MultiPlan, and Quest Diagnostics to fix a common problem, i.e., outdated or inaccurate provider information. They’re using blockchain to create a secure, shared network that keeps provider data accurate and up to date. This strategic move helps reduce administrative headaches, lower costs, and ensure patients get smoother, more reliable care. It’s all about making healthcare data management smarter, faster, and more efficient for everyone involved.

10. Chronicled

Chronicled is a San Francisco-based tech company helping the life sciences industry automate and streamline transactions. In the US, around $500 billion worth of medicines are sold every year, but behind the scenes, companies deal with a lot of back-and-forth, like chargebacks, rebates, and fees, which slows things down. Chronicled solves this using its blockchain-powered MediLedger Network, making these transactions automatic, accurate, and hassle-free. Their first solution, Contracts & Chargebacks, helps pharmaceutical companies settle claims quickly and ensures fair drug pricing for hospitals, pharmacies, and healthcare providers.

Conclusion

The top healthcare companies listed above are proof that blockchain is no longer a futuristic concept. It is the backbone of next-generation healthcare systems. If you want to stay competitive and future-ready, now is the time to explore blockchain adoption.

At Antier, we help medical organizations, hospitals, insurers, and pharmaceutical companies leverage blockchain for healthcare development and achieve next-level efficiency, security, and patient care. Our end-to-end blockchain healthcare development services are tailored to meet your business objectives while ensuring compliance with global healthcare regulations.

Whether you want a drug traceability solution, a smart contract-driven claims processing system, or blockchain healthcare solutions for medical records management, Antier has the technical expertise and industry experience to make it happen.

Contact Antier’s experts today to unlock the potential of blockchain in healthcare!