Top 10 Blockchain Development Companies in the USA

With the blockchain industry projected to grow at a CAGR of 90.1% from 2025 to 2030, there is no doubt that the race to decentralize everything, from finance to infrastructure, has already started. But here’s the reality check: ideas alone don’t build empires, but execution does. Behind every DeFi unicorn or NFT marketplace is a blockchain development company making it all happen.

The USA has emerged as a global launchpad for such innovators, home to firms that don’t just write code, but carve out revolutions. In this blog, we spotlight 10 of the top blockchain development companies in USA that are helping businesses, brands, and creators turn their big ideas into decentralized realities. Whether you’re a startup, a Fortune 500, or somewhere in between, this list could be your first step toward a Web3 breakthrough.

10 Prominent Blockchain Development Companies in USA

The following is the list of blockchain companies in USA that one can walk through to hire a firm that can take their business to new heights in 2025.

1. Antier

Team size: 700+ experts

Established: 2003

Location: India, USA, UK, Australia, and UAE

Backed by a team of 700+ blockchain experts, designers, and engineers, Antier is one of the top blockchain development companies in  USA, which turns complex ideas into powerful, real-world solutions. With a decade of industry experience, the company has successfully delivered 1000+ projects across DeFi, NFTs, and beyond, driving the future of Web3. From startups to enterprises, businesses trust Antier to build scalable, secure, and future-ready digital ecosystems. Partner with Antier as the company’s expertise accelerates impact, and every project takes a step toward tomorrow’s digital revolution.

2. Unicsoft

Team size: 800+ experts

Established: 2005

Location: US

Unicsoft is among the top blockchain development companies in USA that has dedicated the last 10 years to blockchain technology and gained a renowned reputation in the field. Unicsoft is a certified partner of Hedera, Tezos, and Solana and has helped dozens of startups and enterprises tackle business challenges through impactful Web3 solutions. The firm offers an impressively wide range of solutions, including NFT marketplaces, dApps, RWA tokenization platforms, blockchain games, custodial wallets, DePIN systems, and more, that one can avail anytime. With a proven track record, the company excels at delivering superior blockchain-based solutions promptly and reliably.

3. Eva Codes

Team size: 50+ experts

Established: 2019

Location: US, Ukraine, and Portugal

With over 150 finished projects and five-star ratings based on 30+ reviews on Clutch, Eva Codes is a young yet prominent blockchain development company in USA founded in 2019, that helps startups and enterprises pursue Web3 opportunities. The company is well-renowned for its client-oriented approach, rapid delivery, and vibrant web3 community, and this is what helps them stand out from the rest. Eva Codes holds multiple awards, and today, it is considered one of the best blockchain companies in USA by top review sites like Clutch and GoodFirms.

4. MLG Blockchain

Team size: 50+ experts

Established: 2016

Location: US and Canada

MLG Blockchain is an international blockchain advisory and development firm that specializes in end-to-end Web3 solutions and strategic consulting. Based in Toronto and New York, with a remote team spanning over 20 countries, MLG delivers tailored blockchain services to a global clientele. From early-stage proof-of-concepts to full-scale decentralized applications, the firm builds across a variety of blockchain protocols and infrastructures. With a platform-agnostic approach, MLG brings expertise in a wide range of technologies, including Ethereum, Bitcoin, Hyperledger, EOS, Ripple, Tron, Neo, and more. Partnering with such a blockchain app development company in USA means tapping into a deep well of blockchain knowledge to fast-track your journey into the decentralized future.

5. Interexy

Team size: 350+ experts

Established: 2017

Location: USA

Interexy is a trusted innovation partner revolutionizing enterprises with prominent blockchain solutions. With over 7 years of industry expertise and a powerhouse team of 350+ seasoned professionals, they drive digital transformation across the globe. With 300+ clients worldwide, Interexy empowers businesses to stay ahead in the fast-evolving decentralized world. As one of the top blockchain development companies in USA, Interexy provides end-to-end services tailored to your growth goals. If you want to future-proof your business with blockchain, choosing Interexy as your digital partner would be a wise move to lead the next wave of digital disruption!

6. Peiko

Team size:  100+ experts

Established: 2018

Location: USA

Peiko stands as one of the best blockchain companies in USA, known for delivering transformative digital experiences through innovation and expertise. With a mission to bridge the gap between advanced technology and real-world business needs, Peiko empowers enterprises with solutions that are innovative, reliable, scalable, and tailored to solve real-world challenges. Their team of skilled professionals works closely with clients to build customized blockchain applications that drive efficiency, transparency, and growth. Whether you’re a startup or an established enterprise, Peiko can be your trusted partner in building the future of decentralized technology.

7. SpaceDev

Team size:  70+ experts

Established: 2017

Location: Uruguay, Argentina, Colombia, and the United States

Listed among the ‘Top 3 Blockchain Companies’ in the world by Clutch, SpaceDev truly understands the transformative power of decentralization and its impact on global businesses. From blockchain technical research and development to decentralized platforms and Web3 gaming development, SpaceDev offers a wide range of blockchain development services in USA to bring your vision to life. With a rapid MVP development process, a team of top-tier blockchain talent, and a strong focus on delivering real, high-quality results, they’ve helped startups and enterprises alike embrace the future. If you’re looking to innovate, scale, and lead in the decentralized world, collaborate with SpaceDev today!

8. Dexola

Team size: 30+ experts

Established: 2017

Location: USA

Dexola, the autonomous blockchain software development division of Trinetix, is one of the trusted technology partners for Web3 startups and enterprises alike. Since its founding in 2017, Dexola has specialized in building robust blockchain networks and ecosystem applications tailored to client needs. With over eight years of experience, the company has successfully delivered 40+ projects, ranging from DeFi platforms and pay-to-earn games to crypto-based subscription tools and online casinos. As a leading blockchain development company in USA, Dexola prides itself on offering enterprise-level consulting and delivery services while maintaining a flexible, collaborative approach.

9. Innovecs

Team size: 200+ experts

Established: 2011

Location: USA, UK, Israel, and Ukraine

Innovecs is a renowned blockchain development company in USA, recognized for its innovation-driven approach and industry-specific solutions. With expertise across finance, e-commerce, healthcare, and supply chain domains, Innovecs delivers customized blockchain platforms that power secure, scalable, and efficient operations. The company’s portfolio includes peer-to-peer payment systems, KYC compliance tools, credential verification platforms, and enterprise-grade digital wallets. Backed by a team of 200+ engineers across the USA, UK, Israel, and Ukraine, Innovecs emphasizes research, agile development, and end-to-end project delivery. Its commitment to cutting-edge technologies positions clients at the forefront of digital transformation and decentralized innovation.

10. PixelPlex

Team size: 130+ experts

Established: 2007

Location: US

With over a decade of blockchain excellence, PixelPlex transforms bold ideas into powerful digital solutions. Since 2007, PixelPlex has delivered ingenious blockchain-based solutions across fintech, healthcare, real estate, retail, and cybersecurity. Their experienced and skilled development team harnesses blockchain to digitize operations, optimize workflows, & unlock new revenue streams. From research to deployment, the firm handles complex projects with precision and passion. Whether you’re innovating in finance or securing digital assets, PixelPlex is here to bring your vision to life. PixelPlex, one of the top blockchain development companies in USA, leads your business to success with future-ready technology and unmatched expertise.

Conclusion

Today, behind every game-changing dApp, tokenized asset, or decentralized network, there’s a team of thinkers and builders who dared to reimagine the rules through blockchain. The firms featured in this list of top 10 blockchain companies in USA aren’t just following the Web3 wave, but they’re engineering a future where trust is coded into every transaction, ownership is digital and borderless, and innovation flows without intermediaries.

In a world where decentralization holds value, aligning with the ideal blockchain development company in USA is vital. Companies like Antier are digital architects, which are turning complex challenges into scalable, secure realities. They have the right vision and the right team, and your idea could become a reality through their expertise. Contact Antier’s team now and share your project requirements.